Stelara 130mg Injection contains the active substance Ustekinumab. It is a monoclonal antibody that belongs to the group of medications called interleukin inhibitors. Monoclonal antibodies are specific proteins that identify and bind to certain proteins in the body. It treats moderate to severe plaque psoriasis (skin disease with red and scaly patches on some body areas). It is used alone or in combination with other medicines to treat active psoriatic arthritis (a condition that causes joint pain, swelling, and scales on the skin) in adults. Stelara Injection is also indicated to treat moderate to severe Crohn’s disease and ulcerative colitis in adults. Both are inflammatory bowel diseases. Crohn’s disease is a condition in which the body attacks the lining of the digestive tract, causing abdominal pain, diarrhoea, weight loss, and fever. Ulcerative colitis is a condition that causes swelling and sores in the lining of the colon (large intestine) and rectum. Do not use this medicine if you are pregnant or breastfeeding. Do not take Stelara 130mg Injection if you are allergic to Ustekinumab or any of the other ingredients of this medicine. Do not take this medicine if you have any active infections. Inform your doctor if you recently had tuberculosis, skin diseases, allergies, or other diseases. Tell your doctor if you are taking other treatments for psoriasis or psoriatic arthritis. This medicine is not recommended for use in children under 18 years of age with Crohn’s disease or ulcerative colitis.
Stelara (Ustekinumab) 130mg Injection is a monoclonal antibody used to treat inflammatory conditions such as psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. It works by targeting interleukin-12 (IL-12) and interleukin-23 (IL-23), key proteins involved in immune system overactivation and chronic inflammation. By blocking these cytokines, Stelara helps reduce inflammation, alleviate symptoms, and prevent disease progression. In Crohn’s disease and ulcerative colitis, it promotes intestinal healing and improves long-term disease control, while in psoriasis and psoriatic arthritis, it helps reduce skin lesions and joint pain. With less frequent dosing compared to other biologics, Stelara provides a convenient and effective treatment option for patients with moderate to severe inflammatory diseases.
Stelara injection side effects include:
• Severe allergic reactions (anaphylaxis)
• Skin cancer
• Infections
• Lung inflammation and infection
• Heart attack
Stelara injection administration is via intravenous (IV) infusion for the initial dose, followed by subcutaneous (SC) injections for maintenance therapy. The first Stelara injection dose is given as a 130mg IV infusion over at least one hour, typically used for Crohn’s disease and ulcerative colitis. After the initial infusion, maintenance doses are administered as 90mg subcutaneous injections every 8 weeks. It should be given under the supervision of a healthcare professional, and patients must follow their prescribed dosing schedule to ensure optimal treatment effectiveness.
• Breast Feeding: Breastfeeding is not recommended in patients taking Stelara 130mg Injection because the medicine passes into the breast milk in small amounts and may harm your baby.
• Alcohol: It is unknown whether consuming alcohol is safe during the treatment with Stelara 130mg Injection. Inform your doctor if you are a chronic drinker.
• Liver: It is unknown whether Stelara 130mg Injection can be used in patients with liver disorders. Consult your doctor if you have any liver problems before starting the treatment.
• Lungs: It is unknown whether Stelara 130mg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
• Driving: Stelara 130mg Injection does not affect the ability to drive. If you feel tired or dizzy after taking this medicine, do not drive and consult your doctor for more advice.
• Pregnancy: Stelara 130mg Injection is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective contraception during the treatment and for at least 15 weeks after your last dose is necessary